The coronavirus infection rates have fallen in nine out of 10 boroughs of Greater Manchester.
Bolton is the only area in the region where the transmission rate has increased.
Public Health England have released the most up-to-date figures for the seven days ending January 14.
Health experts say England is beginning to see the effects of national lockdown measures.
Yet Prof Powis, NHS medical director, said it would be a number of weeks before current lockdown measures would begin to have an impact on hospital admissions.
The overall infection rate for Greater Manchester is 399.3 for the seven day period ending January 14, and down by 7pc.
It remains lower the national rate of 504.5 per 100,000 people.
While Bolton’s rate is not the highest in the region, it has increased by 4pc to 387.4 cases per 100,000 people.
Manchester still has the highest rate with 449.5 per 100,000. It is a slight decrease of 3pc.
Wigan’s coronavirus infection rate has fallen by 10pc to 422.6 per 100,000. The borough currently has the second highest rate in the region.
Oldham – once one of the worst hit areas by the virus – now has the lowest infection rate in Greater Manchester.
The rate has fallen by 14pc to 314.5 per 100,000 people in the week ending January 14.
Rochdale has recorded the biggest fall in infections. The town’s rate has decreased by 20pc to 339.9 per 100,000.
Tameside’s rate has fallen slightly too 369.1 per 100,000 while Stockport’s dropped by 3pc to 401.1.
The spread of the virus has slowed down in Bury too with a 7pc decrease to 412.1 per 100,000.
The infection rate in Salford is 404.1 and in Trafford it is 415.8.
Eleven more people have sadly died in Greater Manchester’s hospitals after testing positive for coronavirus.
These are cases where a patient has tested positive for the virus within 28 days of their death or where Covid-19 has been mentioned on their death certificate.
In a statement the NHS said: “A further 532 people, who tested positive for the Coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 61,453.
“Patients were aged between 35 and 103 years old.
“All except 21 (aged 40 to 97 years old) had known underlying health conditions.
“Date of death ranges from 13 December to 17 January 2021 with the majority being on or after 10 January.”